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Rosiglitazone.

Without a Prescription

Rosiglitazone is prescribed to treat type 2 diabetes and control sugar blood levels.
Rosiglitazone is prescribed for the treatment of Type II diabetes mellitus.
Rosiglitazone, combined with diet, exercise, weight control and cessation of smoking is prescribed for treating type II diabetes.
Rosiglitazone is prescribed alone or in combination with other types of anti-diabetic drugs such as metformin or sulfonylureas as well as insulin. Since it requires naturally-secreted insulin to be effective, Rosiglitazone is not recommended for use in type I diabetes where the amount of insulin is very low or absent.

Warnings

You may be required to undergo special monitoring or be given dosage adjustments if you are suffering from any of these conditions:
- Edema or water retention / swelling;
- Heart failure or heart disease;
- Liver disease;
- Need to undergo surgery;
- Serious infection illness or injury;
- Type 1 diabetes mellitus;

Side Effects

The most common side effects seen with Rosiglitazone alone or in combination with metformin are:
- Back Pain;
- Fatigue;
- Headache;
- Hyperglycemia;
- Sinusitis Hypoglycemia;
- Upper Respiratory Tract Infection;

Rosiglitazone has been shown to cause mild to moderate accumulation of fluid (edema) and can lead to heart failure. In addition, anemia may occur with Rosiglitazone alone or combined with metformin. Rosiglitazone also causes increasing amounts of weight gain with increasing doses.

Since troglitazone, a related drug, was associated with liver injury, it is recommended that liver tests be obtained before starting therapy and periodically thereafter. Side effects which may suggest liver injury include:
- Abdominal pain;
- Anorexia (loss of appetite);
- Dark urine;
- Fatigue;
- Unexplained nausea;
- Vomiting;

If any of the following conditions is observed, stop usage of Rosiglitazone and call your doctor for the proper medical help:
- Abdominal pain;
- Closing of the throat;
- Dark urine;
- Difficulty in breathing;
- Hives;
- Loss of appetite;
- Nausea;
- Swelling of the lips tongue face;
- Unusual fatigue;
- Vomiting;
- Yellowing of the skin or eyes;

Other less severe side effects would include:
- Sore throat;
- Nasal discharge;
- Headache;
- Cold symptoms;

Overdose

Reported Rosiglitazone overdose symptoms are:
- Fluid retention;
- Liver disease;
- Congestive heart failure (CHF);

Other Brand Names

In some countries Rosiglitazone may also be known as:
- Rosiglizole;
- Avandia;

Form.

Tablets: 2 milligrams,
Tablets: 4 milligrams,
Tablets: 8 milligrams.

Dosage.

Rosiglitazone may be taken once or twice daily, with or without meals. Daily doses range from 4 to 8 milligrams either with or without other antidiabetic medications. Studies do not demonstrate additional effects when more than 8 milligrams per day are taken.

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